Low Oxygen Modulates Multiple Signaling Pathways, Increasing Self-Renewal, While Decreasing Differentiation, Senescence, and Apoptosis in Stromal MIAMI Cells

Human bone marrow multipotent mesenchymal stromal cell (hMSC) number decreases with aging. Subpopulations of hMSCs can differentiate into cells found in bone, vasculature, cartilage, gut, and other tissues and participate in their repair. Maintaining throughout adult life such cell subpopulations sh...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Rios, Carmen, D'Ippolito, Gianluca, Curtis, Kevin M., Delcroix, Gaëtan J.-R., Gomez, Lourdes A., El Hokayem, Jimmy, Rieger, Megan, Parrondo, Ricardo, de las Pozas, Alicia, Perez-Stable, Carlos, Howard, Guy A., Schiller, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892221/
https://ncbi.nlm.nih.gov/pubmed/27059084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0362
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