Fractalkine Receptor Deficiency Is Associated with Early Protection but Late Worsening of Outcome following Brain Trauma in Mice

An impaired ability to regulate microglia activation by fractalkine (CX3CL1) leads to microglia chronic sub-activation. How this condition affects outcome after acute brain injury is still debated, with studies showing contrasting results depending on the timing and the brain pathology. Here, we inv...

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Bibliographic Details
Published in:J Neurotrauma
Main Authors: Zanier, Elisa R., Marchesi, Federica, Ortolano, Fabrizio, Perego, Carlo, Arabian, Maedeh, Zoerle, Tommaso, Sammali, Eliana, Pischiutta, Francesca, De Simoni, Maria-Grazia
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892197/
https://ncbi.nlm.nih.gov/pubmed/26180940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2015.4041
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