Long-lasting protection in brain trauma by endotoxin preconditioning

We investigated the occurrence of endotoxin (lipopolysaccharide, LPS) preconditioning in traumatic brain injury (TBI), evaluating the time window of LPS-induced protection, its persistence, and the associated molecular mechanisms. Mice received 0.1 mg/kg LPS or saline intraperitoneally and subsequen...

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Detalhes bibliográficos
Main Authors: Longhi, Luca, Gesuete, Raffaella, Perego, Carlo, Ortolano, Fabrizio, Sacchi, Noemi, Villa, Pia, Stocchetti, Nino, De Simoni, Maria-Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185879/
https://ncbi.nlm.nih.gov/pubmed/21468087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.42
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