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Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling
EFHC1 encodes a ciliary protein that has been linked to Juvenile Myoclonic Epilepsy. In ectodermal explants, derived from Xenopus laevis embryos, the morpholino-mediated down-regulation of EFHC1b inhibited multiciliated cell formation. In those ciliated cells that did form, axoneme but not basal bod...
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| Udgivet i: | Dev Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892117/ https://ncbi.nlm.nih.gov/pubmed/26783883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.01.004 |
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