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Nmnat1 protects neuronal function without altering phospho‐tau pathology in a mouse model of tauopathy
OBJECTIVE: The nicotinamide‐nucleotide adenylyltransferase protein Nmnat1 is a potent inhibitor of axonal degeneration in models of acute axonal injury. Hyperphosphorylation and aggregation of the microtubule‐associated protein Tau are associated with neurodegeneration in Alzheimer's Disease an...
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| Izdano u: | Ann Clin Transl Neurol |
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| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891997/ https://ncbi.nlm.nih.gov/pubmed/27547771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.308 |
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