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Sensitization of the Hypothalamic-Pituitary-Adrenal Axis in a Male Rat Chronic Stress Model

Stress activation of the hypothalamic-pituitary-adrenal (HPA) axis is regulated by rapid glucocorticoid negative feedback. Chronic unpredictable stress animal models recapitulate certain aspects of major depression in humans, which have been attributed to impaired glucocorticoid negative feedback. W...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Endocrinology
Hauptverfasser: Franco, Alier J., Chen, Chun, Scullen, Tyler, Zsombok, Andrea, Salahudeen, Ahmed A., Di, Shi, Herman, James P., Tasker, Jeffrey G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891782/
https://ncbi.nlm.nih.gov/pubmed/27054552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1641
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