Sensitization of the Hypothalamic-Pituitary-Adrenal Axis in a Male Rat Chronic Stress Model

Stress activation of the hypothalamic-pituitary-adrenal (HPA) axis is regulated by rapid glucocorticoid negative feedback. Chronic unpredictable stress animal models recapitulate certain aspects of major depression in humans, which have been attributed to impaired glucocorticoid negative feedback. W...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Franco, Alier J., Chen, Chun, Scullen, Tyler, Zsombok, Andrea, Salahudeen, Ahmed A., Di, Shi, Herman, James P., Tasker, Jeffrey G.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891782/
https://ncbi.nlm.nih.gov/pubmed/27054552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1641
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