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Gene switching rate determines response to extrinsic perturbations in the self-activation transcriptional network motif
Gene switching dynamics is a major source of randomness in genetic networks, also in the case of large concentrations of the transcription factors. In this work, we consider a common network motif - the positive feedback of a transcription factor on its own synthesis - and assess its response to ext...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891709/ https://ncbi.nlm.nih.gov/pubmed/27256916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26980 |
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