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Gene switching rate determines response to extrinsic perturbations in the self-activation transcriptional network motif
Gene switching dynamics is a major source of randomness in genetic networks, also in the case of large concentrations of the transcription factors. In this work, we consider a common network motif - the positive feedback of a transcription factor on its own synthesis - and assess its response to ext...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891709/ https://ncbi.nlm.nih.gov/pubmed/27256916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26980 |
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