Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level

BACKGROUND: Endoplasmic reticulum disulfide oxidase 1-α (ERO1-α) is an oxidase that exists in the endoplasmic reticulum and has a role in the formation of disulfide bonds of secreted proteins and cell-surface proteins. Recently, we reported that ERO1-α is present in high levels in various types of t...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Tanaka, Tsutomu, Kutomi, Goro, Kajiwara, Toshimitsu, Kukita, Kazuharu, Kochin, Vitaly, Kanaseki, Takayuki, Tsukahara, Tomohide, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Okamoto, Yoshiharu, Hirata, Koichi, Sato, Noriyuki, Tamura, Yasuaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891497/
https://ncbi.nlm.nih.gov/pubmed/27100727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.105
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