Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells

The presentation of an exogenous antigen in a major histocompatibility complex class-I-restricted fashion to CD8(+) T cells is called cross-presentation. Heat shock proteins (HSPs) such as Hsp70, gp96, and Hsp90 have been shown to elicit efficient CTL responses by cross-presentation through an as-ye...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Tanaka, Tsutomu, Okuya, Koichi, Kutomi, Goro, Takaya, Akari, Kajiwara, Toshimitsu, Kanaseki, Takayuki, Tsukahara, Tomohide, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Hirata, Koichi, Okamoto, Yoshiharu, Sato, Noriyuki, Tamura, Yasuaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317773/
https://ncbi.nlm.nih.gov/pubmed/25414129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12570
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