Downregulating hypoxia-inducible factor-1α expression with perfluorooctyl-bromide nanoparticles reduces early brain injury following experimental subarachnoid hemorrhage in rats

The aim of the present study was to investigate the effects of perfluorooctyl-bromide (PFOB) nanoparticles on hypoxia-inducible factor 1 alpha (HIF-1α) and its downstream target genes in early brain injury (EBI) after subarachnoid hemorrhage (SAH). Healthy male Sprague Dawley rats (n=100) were rando...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Xu, Wei, Xu, Rui, Li, Xia, Zhang, Huan, Wang, Xin, Zhu, Ji
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891424/
https://ncbi.nlm.nih.gov/pubmed/27347319
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