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Downregulating hypoxia-inducible factor-1α expression with perfluorooctyl-bromide nanoparticles reduces early brain injury following experimental subarachnoid hemorrhage in rats

The aim of the present study was to investigate the effects of perfluorooctyl-bromide (PFOB) nanoparticles on hypoxia-inducible factor 1 alpha (HIF-1α) and its downstream target genes in early brain injury (EBI) after subarachnoid hemorrhage (SAH). Healthy male Sprague Dawley rats (n=100) were rando...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Xu, Wei, Xu, Rui, Li, Xia, Zhang, Huan, Wang, Xin, Zhu, Ji
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891424/
https://ncbi.nlm.nih.gov/pubmed/27347319
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