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MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR

The Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded chemokine receptor vGPCR acts as an oncogene in Kaposi's sarcomagenesis. Until now, the molecular mechanisms by which the vGPCR contributes to tumor development remain incompletely understood. Here, we show that the KSHV-vGPCR cont...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Krause, Claudia J., Popp, Oliver, Thirunarayanan, Nanthakumar, Dittmar, Gunnar, Lipp, Martin, Müller, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891129/
https://ncbi.nlm.nih.gov/pubmed/26871287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7248
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