Pan-cancer analysis of intratumor heterogeneity as a prognostic determinant of survival

As tumors accumulate genetic alterations, an evolutionary process occurs in which genetically distinct subclonal populations of cells co-exist, resulting in intratumor genetic heterogeneity (ITH). The clinical implications of ITH remain poorly defined. Data are limited with respect to whether ITH is...

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Vydáno v:Oncotarget
Hlavní autoři: Morris, Luc G.T., Riaz, Nadeem, Desrichard, Alexis, Şenbabaoğlu, Yasin, Hakimi, A. Ari, Makarov, Vladimir, Reis-Filho, Jorge S., Chan, Timothy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891103/
https://ncbi.nlm.nih.gov/pubmed/26840267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7067
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