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Cold inducible RNA binding protein upregulation in pituitary corticotroph adenoma induces corticotroph cell proliferation via Erk signaling pathway

Cushing's disease is caused by pituitary corticotroph adenoma, and the pathogenesis of it has remained obscure. Here, we showed that cold inducible RNA binding protein (CIRP) was markedly elevated in corticotroph tumors. Forced overexpression of CIRP in murine AtT20 pituitary corticotroph cell...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Jian, Fangfang, Chen, Yufan, Ning, Guang, Fu, Wei, Tang, Hao, Chen, Xiao, Zhao, Yao, Zheng, Lili, Pan, Sijian, Wang, Weiqing, Bian, Liuguan, Sun, Qingfang
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891034/
https://ncbi.nlm.nih.gov/pubmed/26824322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7037
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