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Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations
The activity of the M isoform of microphthalmia-associated transcription factor (MITF-M) has been attributed to regulation of differentiation, proliferation, survival and senescence of melanoma cells. MITF expression was shown to be antagonized by the activation of transcription factor NF-κB. Parthe...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891023/ https://ncbi.nlm.nih.gov/pubmed/26824319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7030 |
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