Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations

The activity of the M isoform of microphthalmia-associated transcription factor (MITF-M) has been attributed to regulation of differentiation, proliferation, survival and senescence of melanoma cells. MITF expression was shown to be antagonized by the activation of transcription factor NF-κB. Parthe...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Hartman, Mariusz L., Talar, Beata, Sztiller-Sikorska, Malgorzata, Nejc, Dariusz, Czyz, Malgorzata
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891023/
https://ncbi.nlm.nih.gov/pubmed/26824319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7030
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