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Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres

Growing evidence suggests that the cancer stem cell phenotype in melanoma is dynamically regulated. Therefore, effective therapies have to target simultaneously bulk tumor cells and melanoma stem-like cells. The aim of the present study was to investigate the effects of parthenolide on heterogeneous...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Czyz, Malgorzata, Koprowska, Kamila, Sztiller-Sikorska, Malgorzata
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571995/
https://ncbi.nlm.nih.gov/pubmed/23192276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.22952
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