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TERT promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas

Increasing evidences have implicated somatic gain-of-function mutations at the telomerase reverse transcriptase (TERT) promoter as one of the major mechanisms that promote transcriptional activation of TERT and subsequently maintain telomere length in human cancers including glioma. To investigate t...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Gao, Ke, Li, Gang, Qu, Yiping, Wang, Maode, Cui, Bo, Ji, Meiju, Shi, Bingyin, Hou, Peng
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890999/
https://ncbi.nlm.nih.gov/pubmed/26556853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6007
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