GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis

The glucocorticoid-induced TNFR family-related protein (GITR) and its ligand play a critical role in the pathogenesis of autoimmune arthritis by enhancing the Th17 cell response, but their molecular mechanisms remain largely unclear. This study aims to define the role of p38 mitogen-activated protei...

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Pubblicato in:Oncotarget
Autori principali: Tang, Xinyi, Tian, Jie, Ma, Jie, Wang, Jiemin, Qi, Chen, Rui, Ke, Wang, Yungang, Xu, Huaxi, Lu, Liwei, Wang, Shengjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper: Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890989/
https://ncbi.nlm.nih.gov/pubmed/26657118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6535
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