Receptor Binding by Cholera Toxin B-Subunit and Amino Acid Modification Improves Minimal Peptide Immunogenicity

We increase our understanding of augmenting a cellular immune response, by using an HIV-1 protease-derived epitope (PR(75–84)), and variants thereof, coupled to the C-terminal, of the B subunit of cholera toxin (CTB). Fusion proteins were used for immunizations of HLA-A0201 transgenic C57BL/6 mice....

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Detalhes bibliográficos
Publicado no:ISRN Mol Biol
Main Authors: Boberg, Andreas, Stålnacke, Alexandra, Bråve, Andreas, Hinkula, Jorma, Wahren, Britta, Carlin, Nils
Formato: Artigo
Idioma:Inglês
Publicado em: International Scholarly Research Network 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890861/
https://ncbi.nlm.nih.gov/pubmed/27335661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/170676
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