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Reduction in oral immunogenicity of cholera toxin B subunit by N-terminal peptide addition.

The mucosal adjuvanticity of cholera toxin and the potential of the B subunit of cholera toxin (CtxB) to serve as an oral vaccine carrier have prompted interest in the coupling of immunogenic peptides to this protein. The purpose of this study was to determine how such fusions affect the function of...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Dertzbaugh, M T, Elson, C O
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1993
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302741/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8423068/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.2.384-390.1993
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