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Reduction in oral immunogenicity of cholera toxin B subunit by N-terminal peptide addition.

The mucosal adjuvanticity of cholera toxin and the potential of the B subunit of cholera toxin (CtxB) to serve as an oral vaccine carrier have prompted interest in the coupling of immunogenic peptides to this protein. The purpose of this study was to determine how such fusions affect the function of...

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Vydáno v:Infect Immun
Hlavní autoři: Dertzbaugh, M T, Elson, C O
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302741/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8423068/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.2.384-390.1993
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