Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound

In staphylococci, quorum sensing regulates both biofilm formation and toxin production, moreover it has been demonstrated to be inhibited by RNAIII inhibiting peptide (RIP). Aim our study was to evaluate the in vitro activity and its in vivo efficacy of the combined administration of FS10, a novel R...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Simonetti, Oriana, Cirioni, Oscar, Cacciatore, Ivana, Baldassarre, Leonardo, Orlando, Fiorenza, Pierpaoli, Elisa, Lucarini, Guendalina, Orsetti, Elena, Provinciali, Mauro, Fornasari, Erika, Di Stefano, Antonio, Giacometti, Andrea, Offidani, Annamaria
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890846/
https://ncbi.nlm.nih.gov/pubmed/27253706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151956
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