Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound

In staphylococci, quorum sensing regulates both biofilm formation and toxin production, moreover it has been demonstrated to be inhibited by RNAIII inhibiting peptide (RIP). Aim our study was to evaluate the in vitro activity and its in vivo efficacy of the combined administration of FS10, a novel R...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Simonetti, Oriana, Cirioni, Oscar, Cacciatore, Ivana, Baldassarre, Leonardo, Orlando, Fiorenza, Pierpaoli, Elisa, Lucarini, Guendalina, Orsetti, Elena, Provinciali, Mauro, Fornasari, Erika, Di Stefano, Antonio, Giacometti, Andrea, Offidani, Annamaria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890846/
https://ncbi.nlm.nih.gov/pubmed/27253706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151956
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