Modeling and Re-Engineering of Azotobacter vinelandii Alginate Lyase to Enhance Its Catalytic Efficiency for Accelerating Biofilm Degradation

Alginate is known to prevent elimination of Pseudomonas aeruginosa biofilms. Alginate lyase (AlgL) might therefore facilitate treatment of Pseudomonas aeruginosa-infected cystic fibrosis patients. However, the catalytic activity of wild-type AlgL is not sufficiently high. Therefore, molecular modeli...

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Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Jang, Chul Ho, Piao, Yu Lan, Huang, Xiaoqin, Yoon, Eun Jeong, Park, So Hee, Lee, Kyoung, Zhan, Chang-Guo, Cho, Hoon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890793/
https://ncbi.nlm.nih.gov/pubmed/27253324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156197
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