Withaferin A protects against palmitic acid-induced endothelial insulin resistance and dysfunction through suppression of oxidative stress and inflammation

Activation of inflammatory pathways via reactive oxygen species (ROS) by free fatty acids (FFA) in obesity gives rise to insulin resistance and endothelial dysfunction. Withaferin A (WA), possesses both antioxidant and anti-inflammatory properties and therefore would be a good strategy to suppress p...

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Vydáno v:Sci Rep
Hlavní autoři: Batumalaie, Kalaivani, Amin, Muhammad Arif, Murugan, Dharmani Devi, Sattar, Munavvar Zubaid Abdul, Abdullah, Nor Azizan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890118/
https://ncbi.nlm.nih.gov/pubmed/27250532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27236
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