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Withaferin A protects against palmitic acid-induced endothelial insulin resistance and dysfunction through suppression of oxidative stress and inflammation

Activation of inflammatory pathways via reactive oxygen species (ROS) by free fatty acids (FFA) in obesity gives rise to insulin resistance and endothelial dysfunction. Withaferin A (WA), possesses both antioxidant and anti-inflammatory properties and therefore would be a good strategy to suppress p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Batumalaie, Kalaivani, Amin, Muhammad Arif, Murugan, Dharmani Devi, Sattar, Munavvar Zubaid Abdul, Abdullah, Nor Azizan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890118/
https://ncbi.nlm.nih.gov/pubmed/27250532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27236
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