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Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks

Alternative splicing is regulated by multiple RNA-binding proteins and influences the expression of most eukaryotic genes. However, the role of this process in human disease, and particularly in cancer, is only starting to be unveiled. We systematically analyzed mutation, copy number, and gene expre...

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Publicat a:Genome Res
Autors principals: Sebestyén, Endre, Singh, Babita, Miñana, Belén, Pagès, Amadís, Mateo, Francesca, Pujana, Miguel Angel, Valcárcel, Juan, Eyras, Eduardo
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889968/
https://ncbi.nlm.nih.gov/pubmed/27197215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.199935.115
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