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Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks

Alternative splicing is regulated by multiple RNA-binding proteins and influences the expression of most eukaryotic genes. However, the role of this process in human disease, and particularly in cancer, is only starting to be unveiled. We systematically analyzed mutation, copy number, and gene expre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Res
Egile Nagusiak: Sebestyén, Endre, Singh, Babita, Miñana, Belén, Pagès, Amadís, Mateo, Francesca, Pujana, Miguel Angel, Valcárcel, Juan, Eyras, Eduardo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889968/
https://ncbi.nlm.nih.gov/pubmed/27197215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.199935.115
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