Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex

The Fanconi anemia protein SLX4 assembles a genome and telomere maintenance toolkit, consisting of the nucleases SLX1, MUS81 and XPF. Although it is known that SLX4 acts as a scaffold for building this complex, the molecular basis underlying this function of SLX4 remains unclear. Here, we report tha...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Yin, Jinhu, Wan, Bingbing, Sarkar, Jaya, Horvath, Kent, Wu, Jian, Chen, Yong, Cheng, Guangjuan, Wan, Ke, Chin, Peiju, Lei, Ming, Liu, Yie
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889959/
https://ncbi.nlm.nih.gov/pubmed/27131364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw354
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