Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor

Cell differentiation is a central process in development and in cancer growth and dissemination. OCT4 (POU5F1) and NANOG are essential for cell stemness and pluripotency; yet, the mechanisms that regulate their expression remain largely unknown. Repetitive elements account for almost half of the Hum...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Morales-Hernández, Antonio, González-Rico, Francisco J., Román, Angel C., Rico-Leo, Eva, Alvarez-Barrientos, Alberto, Sánchez, Laura, Macia, Ángela, Heras, Sara R., García-Pérez, José L., Merino, Jaime M., Fernández-Salguero, Pedro M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889919/
https://ncbi.nlm.nih.gov/pubmed/26883630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw095
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