An EP2 Agonist Facilitates NMDA-Induced Outward Currents and Inhibits Dendritic Beading through Activation of BK Channels in Mouse Cortical Neurons

Prostaglandin E(2) (PGE(2)), a major metabolite of arachidonic acid produced by cyclooxygenase pathways, exerts its bioactive responses by activating four E-prostanoid receptor subtypes, EP1, EP2, EP3, and EP4. PGE(2) enables modulating N-methyl-D-aspartate (NMDA) receptor-mediated responses. Howeve...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Hayashi, Yoshinori, Morinaga, Saori, Liu, Xia, Zhang, Jing, Wu, Zhou, Yokoyama, Takeshi, Nakanishi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889853/
https://ncbi.nlm.nih.gov/pubmed/27298516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5079597
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