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Molecular mechanisms of statin intolerance

Statins reduce cardiovascular morbidity and mortality in primary and secondary prevention. Despite their efficacy, many persons are unable to tolerate statins due to adverse events such as hepatotoxicity and myalgia/myopathy. In the case of most patients, it seems that mild-to-moderate abnormalities...

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Détails bibliographiques
Publié dans:Arch Med Sci
Auteurs principaux: Gluba-Brzozka, Anna, Franczyk, Beata, Toth, Peter P., Rysz, Jacek, Banach, Maciej
Format: Artigo
Langue:Inglês
Publié: Termedia Publishing House 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889699/
https://ncbi.nlm.nih.gov/pubmed/27279860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2016.59938
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