Molecular mechanisms of statin intolerance

Statins reduce cardiovascular morbidity and mortality in primary and secondary prevention. Despite their efficacy, many persons are unable to tolerate statins due to adverse events such as hepatotoxicity and myalgia/myopathy. In the case of most patients, it seems that mild-to-moderate abnormalities...

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Bibliographic Details
Published in:Arch Med Sci
Main Authors: Gluba-Brzozka, Anna, Franczyk, Beata, Toth, Peter P., Rysz, Jacek, Banach, Maciej
Format: Artigo
Language:Inglês
Published: Termedia Publishing House 2016
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State of the Art Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889699/
https://ncbi.nlm.nih.gov/pubmed/27279860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2016.59938
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