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Expression of tandem gene duplicates is often greater than twofold

Tandem gene duplication is an important mutational process in evolutionary adaptation and human disease. Hypothetically, two tandem gene copies should produce twice the output of a single gene, but this expectation has not been rigorously investigated. Here, we show that tandem duplication often res...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Loehlin, David W., Carroll, Sean B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889415/
https://ncbi.nlm.nih.gov/pubmed/27162370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605886113
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