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Expression of tandem gene duplicates is often greater than twofold

Tandem gene duplication is an important mutational process in evolutionary adaptation and human disease. Hypothetically, two tandem gene copies should produce twice the output of a single gene, but this expectation has not been rigorously investigated. Here, we show that tandem duplication often res...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Loehlin, David W., Carroll, Sean B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889415/
https://ncbi.nlm.nih.gov/pubmed/27162370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605886113
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