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Primer release is the rate-limiting event in lagging-strand synthesis mediated by the T7 replisome
DNA replication occurs semidiscontinuously due to the antiparallel DNA strands and polarity of enzymatic DNA synthesis. Although the leading strand is synthesized continuously, the lagging strand is synthesized in small segments designated Okazaki fragments. Lagging-strand synthesis is a complex eve...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889403/ https://ncbi.nlm.nih.gov/pubmed/27162371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604894113 |
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