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Type IV pilins regulate their own expression via direct intramembrane interactions with the sensor kinase PilS
Type IV pili are important virulence factors for many pathogens, including Pseudomonas aeruginosa. Transcription of the major pilin gene—pilA—is controlled by the PilS-PilR two-component system in response to unknown signals. The absence of a periplasmic sensing domain suggested that PilS may sense...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889343/ https://ncbi.nlm.nih.gov/pubmed/27162347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512947113 |
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