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Type IV pilins regulate their own expression via direct intramembrane interactions with the sensor kinase PilS

Type IV pili are important virulence factors for many pathogens, including Pseudomonas aeruginosa. Transcription of the major pilin gene—pilA—is controlled by the PilS-PilR two-component system in response to unknown signals. The absence of a periplasmic sensing domain suggested that PilS may sense...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kilmury, Sara L. N., Burrows, Lori L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889343/
https://ncbi.nlm.nih.gov/pubmed/27162347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512947113
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