Augmentation of angiotensinogen expression in the proximal tubule by intracellular angiotensin II via AT(1a)/MAPK/NF-кB signaling pathways

Long-term angiotensin II (ANG II) infusion significantly increases ANG II levels in the kidney through two major mechanisms: AT(1) receptor-mediated augmentation of angiotensinogen (AGT) expression and uptake of circulating ANG II by the proximal tubules. However, it is not known whether intracellul...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Zhuo, Jia L., Kobori, H., Li, Xiao C., Satou, R., Katsurada, A., Navar, L. Gabriel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889322/
https://ncbi.nlm.nih.gov/pubmed/26864937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00350.2015
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