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CDKIs p18(INK4c) and p57(Kip2) are involved in quiescence of CML leukemic stem cells after treatment with TKI
Chronic Myeloid Leukemia (CML) is sustained by a small population of cells with stem cell characteristics known as Leukemic Stem Cells that are positive to BCR-ABL fusion protein, involved with several abnormalities in cell proliferation, expansion, apoptosis and cell cycle regulation. Current treat...
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發表在: | Cell Cycle |
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Main Authors: | , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Taylor & Francis
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889309/ https://ncbi.nlm.nih.gov/pubmed/26985855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1160976 |
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