CDKIs p18(INK4c) and p57(Kip2) are involved in quiescence of CML leukemic stem cells after treatment with TKI

Chronic Myeloid Leukemia (CML) is sustained by a small population of cells with stem cell characteristics known as Leukemic Stem Cells that are positive to BCR-ABL fusion protein, involved with several abnormalities in cell proliferation, expansion, apoptosis and cell cycle regulation. Current treat...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Moreno-Lorenzana, Dafne, Avilés-Vazquez, Sócrates, Sandoval Esquivel, Miguel Angel, Alvarado-Moreno, Antonio, Ortiz-Navarrete, Vianney, Torres-Martínez, Héctor, Ayala-Sánchez, Manuel, Mayani, Héctor, Chavez-Gonzalez, Antonieta
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889309/
https://ncbi.nlm.nih.gov/pubmed/26985855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1160976
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