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PrimPol-deficient cells exhibit a pronounced G2 checkpoint response following UV damage
PrimPol is a recently identified member of the archaeo-eukaryote primase (AEP) family of primase-polymerases. It has been shown that this mitochondrial and nuclear localized enzyme plays roles in the maintenance of both unperturbed replication fork progression and in the bypass of lesions after DNA...
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Publié dans: | Cell Cycle |
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Auteurs principaux: | , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Taylor & Francis
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889237/ https://ncbi.nlm.nih.gov/pubmed/26694751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1128597 |
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