PrimPol-deficient cells exhibit a pronounced G2 checkpoint response following UV damage

PrimPol is a recently identified member of the archaeo-eukaryote primase (AEP) family of primase-polymerases. It has been shown that this mitochondrial and nuclear localized enzyme plays roles in the maintenance of both unperturbed replication fork progression and in the bypass of lesions after DNA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Cycle
Egile Nagusiak: Bailey, Laura J., Bianchi, Julie, Hégarat, Nadia, Hochegger, Helfrid, Doherty, Aidan J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889237/
https://ncbi.nlm.nih.gov/pubmed/26694751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1128597
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