PrimPol-deficient cells exhibit a pronounced G2 checkpoint response following UV damage

PrimPol is a recently identified member of the archaeo-eukaryote primase (AEP) family of primase-polymerases. It has been shown that this mitochondrial and nuclear localized enzyme plays roles in the maintenance of both unperturbed replication fork progression and in the bypass of lesions after DNA...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Bailey, Laura J., Bianchi, Julie, Hégarat, Nadia, Hochegger, Helfrid, Doherty, Aidan J.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889237/
https://ncbi.nlm.nih.gov/pubmed/26694751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1128597
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