Local Application of Leptin Antagonist Attenuates Angiotensin II–Induced Ascending Aortic Aneurysm and Cardiac Remodeling

BACKGROUND: Ascending thoracic aortic aneurysm (ATAA) is driven by angiotensin II (AngII) and contributes to the development of left ventricular (LV) remodeling through aortoventricular coupling. We previously showed that locally available leptin augments AngII‐induced abdominal aortic aneurysms in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Am Heart Assoc
Päätekijät: Ben‐Zvi, Danny, Savion, Naphtali, Kolodgie, Frank, Simon, Amos, Fisch, Sudeshna, Schäfer, Katrin, Bachner‐Hinenzon, Noa, Cao, Xin, Gertler, Arieh, Solomon, Gili, Kachel, Erez, Raanani, Ehud, Lavee, Jacob, Kotev Emeth, Shlomo, Virmani, Renu, Schoen, Frederick J., Schneiderman, Jacob
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889208/
https://ncbi.nlm.nih.gov/pubmed/27143353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003474
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