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Local Application of Leptin Antagonist Attenuates Angiotensin II–Induced Ascending Aortic Aneurysm and Cardiac Remodeling
BACKGROUND: Ascending thoracic aortic aneurysm (ATAA) is driven by angiotensin II (AngII) and contributes to the development of left ventricular (LV) remodeling through aortoventricular coupling. We previously showed that locally available leptin augments AngII‐induced abdominal aortic aneurysms in...
Gespeichert in:
Veröffentlicht in: | J Am Heart Assoc |
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Hauptverfasser: | , , , , , , , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
John Wiley and Sons Inc.
2016
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889208/ https://ncbi.nlm.nih.gov/pubmed/27143353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003474 |
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