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Base J Glucosyltransferase does not regulate the sequence specificity of J synthesis in trypanosomatid telomeric DNA

Telomeric DNA of Trypanosomatids possesses a modified thymine base, called base J, that is synthesized in a two-step process; the base is hydroxylated by a thymidine hydroxylase forming hydroxymethyluracil (hmU) and a glucose moiety is then attached by the J-associated glucosyltransferase (JGT). To...

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Detalhes bibliográficos
Publicado no:Mol Biochem Parasitol
Main Authors: Bullard, Whitney, Cliffe, Laura, Wang, Pengcheng, Wang, Yinsheng, Sabatini, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889113/
https://ncbi.nlm.nih.gov/pubmed/26815240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2016.01.005
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