Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense

Mycobacterium tuberculosis (Mtb) must cope with exogenous oxidative stress imposed by the host. Unlike other antioxidant enzymes, Mtb’s thioredoxin reductase TrxB2 has been predicted to be essential not only to fight host defenses but also for in vitro growth. However, the specific physiological rol...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Lin, Kan, O'Brien, Kathryn M., Trujillo, Carolina, Wang, Ruojun, Wallach, Joshua B., Schnappinger, Dirk, Ehrt, Sabine
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889078/
https://ncbi.nlm.nih.gov/pubmed/27249779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005675
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